Most of the wounds heal with normal wound care at the primary level, but some wounds like Non Healing Ulcers, Diabetic foot, Degloving injuries, Venous ulcers, Arterial insuf?ciency ulcers, Wound requiring Cosmetic stitching etc. require specialized care. There are various newer modalities of treatment which help in wound healing. Treatments like vacuum assisted healing closure, specialized lasers, injection of growth factors, Adipose tissue derived stem cells, Mesenchymal cell fractions etc. have added to the existing techniques likeperforator flap, microvascular flaps, muscle flaps & soon.